Principles of Allergy Diagnosis
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چکیده
Allergic diseases are manifest as intestinal (GI) tract. This hyperresponsiveness may have both IgE-mediated and non-IgE-mediated components (Fig. 4). The situation is further complicated because allergen exposure in allergic subjects may increase target organ hyperresponsiveness, which results in exaggerated symptoms on exposure to nonspecific irritants (tobacco smoke, changes in temperature, etc.) in allergic subjects. Furthermore, increased nonspecific responsiveness lowers the threshold for symptoms on subsequent allergen exposure (Fig. 5).
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